Role of Pregabalin to Decrease Postoperative Pain in Microdiscectomy: A Randomized Clinical Trial
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چکیده
منابع مشابه
Preventive Gabapentin versus Pregabalin to Decrease Postoperative Pain after Lumbar Microdiscectomy: A Randomized Controlled Trial
STUDY DESIGN Randomized controlled trial. PURPOSE The purpose of this study was to compare pregabalin and gabapentin for mean postoperative visual analog score (VAS) for pain in patients undergoing single-level lumbar microdiscectomy for intervertebral disc prolapse at a tertiary care hospital. OVERVIEW OF LITERATURE Pregabalin has a superior pharmacokinetic profile and analgesic effect at ...
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background gabapentin is an anticonvulsant that has postoperative analgesic effects but there are limited studies on its postoperative administration. objectives the present study was conducted to evaluate the effect of the postoperative oral gabapentin on pain and morphine consumption. patients and methods in a double blind, randomized study, 64 patients undergoing internal fixation of tibia u...
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knee surgery. The purpose of this study was to assess the analgesic effects of intra-articular injection of a dexmedetomidine following knee arthroscopy. Methods: Forty six patients schadualed for arthroscopic knee surgery under general anaesthesia, were randomly devided into two groups. Intervention group received 1μg/kg dexmedetomidine (D) and isotonic saline. Control group received 25ml is...
متن کاملPostoperative Gabapentin to Prevent Postoperative Pain: A Randomized Clinical Trial
BACKGROUND Gabapentin is an anticonvulsant that has postoperative analgesic effects but there are limited studies on its postoperative administration. OBJECTIVES The present study was conducted to evaluate the effect of the postoperative oral gabapentin on pain and morphine consumption. PATIENTS AND METHODS In a double blind, randomized study, 64 patients undergoing internal fixation of tib...
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BACKGROUND Pregabalin is a potent ligand for alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system, which exhibits potent anticonvulsant, analgesic and anxiolytic activity. The pharmacological activity of pregabalin is similar to that of gabapentin and shows possible advantages. Although it shows analgesic efficacy against neuropathic pain, very limited evidence ...
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ژورنال
عنوان ژورنال: Cureus
سال: 2021
ISSN: 2168-8184
DOI: 10.7759/cureus.12870